参附注射液对重症急性胰腺炎患者血浆IL-1、IL-6表达的影响
肖志英,朱军华,何静,唐碧波
摘要(Abstract)：
目的观察参附注射液对重症急性胰腺炎(SAP)的治疗作用。方法将40例SAP患者按随机原则分为治疗组与对照组各20例,均采用西医常规治疗,治疗组在此基础上加用参附注射液入液静滴,连用7 d。检测治疗前后白细胞介素(IL-1、IL-6)含量,观察两组多器官功能障碍综合征(MODS)发生率、感染中转手术率、病死率及平均住院时间。结果治疗组患者经治疗后各时间点血清中IL-1、IL-6含量均较治疗前明显下降,并明显低于同时间点的对照组;治疗组平均ICU治疗时间(d)、平均住院时间(d)、MODS发生率、感染中转手术率及病死率均较对照组明显降低。结论参附注射液能抑制炎症介质及细胞因子的释放,减轻SIRS,降低MODS的发生率,从而改善预后。
关键词(KeyWords)： 参附注射液;重症急性胰腺炎;白细胞介素-1;白细胞介素-6
基金项目(Foundation):
作者(Author): 肖志英,朱军华,何静,唐碧波
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