功能磁共振成像在针灸研究中的应用与思考Application and Thinking of Functional Magnetic Resonance Imaging(fMRI) on the Research of Acupuncture
滕晶,彭伟
摘要(Abstract)：
功能磁共振是近年来发展起来的一种新的影像技术,可以对大脑的高级功能变化进行可视性研究,其出现为针灸机理的研究提供了有效的研究手段。本文主要总结了近年来功能磁共振在针灸研究中的应用,并对其今后的发展作一论述。
关键词(KeyWords)： 功能磁共振成像;针灸
基金项目(Foundation): 国家自然科学基金资助项目(No.30672755)
作者(Author): 滕晶,彭伟
参考文献(References)：
- 1王苇,朱芳,漆剑频,等.人脑对针刺与对指反应的实时动态功能M RI的对比研究[J].中华放射学杂志,2002,36(3):211
- 2Cho ZH,Chung SC,Jones JP,etal.New findings ofthe correla-tion between acupoints and corresponding brain cortices using functionalM RI[J].Proc NatlAcad SciUSA,1998,95(5):2670～2673
- 3W u M T,Sheen JM,Chuang KH,etal.Neuronalspecificity of acupuncturere sponse:a fM RIstudy with electroacupuncture[J].Neuro Im aging,2002,16(4):1028～1037
- 4SiedentopfCM,GolaszewskiSM,M ottaghy FM,elal.Functional m agnetic resonance im aging detect sactivation of the visual as-sociation cortex during laser acupuncture ofthe footin hum ans[J].NeurosciLett,2002,327(1):53～56
- 5VogtBA,Derbyshire S,Jones AK.Pain processing in four re-gions ofhum an cingulated cortex localized with coregistered PET and M R im aging.Eur JN Eurosci,1996,8(7):1461
- 6张淑倩,刘连祥,吴杰,等.人脑视皮质功能M RI的初步研究及临床应用[J].中华放射学杂志,2001,35(7):524
- 7Lang PI,Bradley M M,Fitzsim m ons JR,etal.Em otionalarousal and activation ofthe visualcortex:an fM RI analysis[J].Psy-chophysiology,1998,35(2):199
- 8李洁巍,张云亭.刺激穴位激活语言皮质的fM RI研究[J].临床放射学杂志,2005,24(12):1039～1043
- 9Geng Li,Chung RTF,W ong KK,et al.A functional M RI study com paring brain activation between word generation and elec-trical:Stim ulation of language im plicated acupoints[J].心理学报,2002,34(1):33
- 10H ui KK,Liu J,M akris N,et al.Acupuncture m odulates the lim bic system and subcortical gray structures of the hum an brain:evidence from fM RI studies innorm al subjects[J].H um Brain M app,2000,9(1):13～25
- 11Biella C,Sorgiu M L,Pellegata C,et al.Acupuncture produces central activations in pain regions[J].Neuro Im age,2001,14(1):60～66
- 12侯金文,黄蔚皓,王青,等.针刺镇痛的脑功能M RI研究[J].中华放射学杂志,2002,36(3):206
- 13许建阳,王发强,陈燕,等.针刺治疗老年性痴呆及脑功能成像的研究.武警医学[J].2003,14(1):4～6
- 14常时新,孔祥泉,李刚,等.多穴位联合电针刺激对卒中恢复期皮层功能变的fM RI的监测[J].中国中西医结合影像学杂志,2003,1(1):10～12
- 15金真,张蔚婷,罗非,等.人脑对不同频率穴位电刺激的功能性磁共振成像[J].生理学报,2001,53(4):275～280
- 16Zhang W T,Jin Z,CuiGH,etal.Relations between Brain Net-work Activation and Analgesic Effect Induced by Low vs H igh Frequency ElectricalAcupointStim ulation in DifferenctSubject s:a FunctionalM agnetic Resonance Im aging Study[J].Brain Research,2003,982(2):168～178
- 17Shen J,DanielR,Reia M,etal.Differentialtim e course ofbrain activation during electro-acupuncture[C].Neuroim age H um an M apping,2000:740
- 18W u M T,H sieh JC,Xiong J,etal.Centralnervous pathway for acupuncture stim ulation:localization of processing with func-tional M R im aging of the brain-prelim inary experience[J].Radiology,1999,212(1):133～141
- 19李定忠,李秀章.经皮部挑治与深刺的fM RI对比研究[J].中国针灸,2000,20(8):491～492
- 20张苗海.运动功能性磁共振成像分析针灸对中枢的作用[J].国外医学·中医中药分册,2003,25(5):283～285