中药对烫伤大鼠肠粘膜屏障的保护作用实验研究
郭力,刘承荣,刘正玉,熊爱兵,蒋灵芝,郑福荣
摘要(Abstract):
采用大鼠30只,复制背部烫伤模型,随机分为治疗组、对照组和正常组。治疗组管饲中药煎剂,对照组和正常组管饲注射用水,定时活杀。测定血浆和回肠粘膜肿瘤坏死因子(TNF)浓度和脏器以及肠系膜淋巴结细菌培养、心血培养,应用光镜、电镜观察回肠粘膜病理改变。结果显示:治疗组血浆和回肠粘膜TNF浓度、内脏组织细菌培养阳性率与对照组相比有显著差异(P<0.05),回肠粘膜病理形态改变也以对照组较重。结论:大鼠烫伤后管饲中药可减轻肠粘膜的损害,并对防治肠道细菌移位有积极作用。
关键词(KeyWords): 烫伤;肠粘膜;中药
基金项目(Foundation):
作者(Author): 郭力,刘承荣,刘正玉,熊爱兵,蒋灵芝,郑福荣
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