从“热毒滞络”论述特发性肺纤维化急性加重期证治Discussion on the Acute exacerbation of Idiopathic Pulmonary Fibrosis from the Perspective of "Heat toxin stagnant collaterals"
黄婧文,张兴彩
摘要(Abstract):
特发性肺纤维化急性加重(AE-IPF)是特发性肺纤维化患者死亡的主要原因,尚无有效治疗措施,给个人及社会造成沉重的负担。本文从络病、伏邪致病、“阴火”理论认识该病:“热毒滞络”是AE-IPF病机;痰瘀伏络、渐成热毒、伏而后发,“阴火”上升、肺受火侮是导致“热毒滞络”并造成急性加重的机制。治疗上分别采用升降散加味以清透伏热、凉血解毒,人参平肺散加味以降气散火、补气升阳。
关键词(KeyWords): 特发性肺纤维化急性加重;肺络;伏邪;阴火;热毒滞络;升降散;人参平肺散
基金项目(Foundation): 国家自然科学基金应急管理项目(81641190);; 山东省医药卫生科技发展计划项目(2015WS0139);; 山东省自然科学基金面上项目(ZR2020MH351)
作者(Author): 黄婧文,张兴彩
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