川芎嗪对肺动脉高压心肺功能的影响
马德娴,熊旭东
摘要(Abstract)：
<正> 肺动脉高压(PAH)是慢性肺源性心脏病发生发展的病理学基础,它的严重程度直接影响肺心病患者的病程、生活质量和预后。降低肺动脉高压,逆转肺血管的病理变化是目前肺心病治疗研究的重点之一。 理想的肺血管扩张剂应具备如下条件:(1)使肺血管阻力降低20％以上;(2)使心输出量增加或无变化;(3)使肺动脉压下降或无变化;(4)使体循环压无改变或下降,但不引起低血压症状[1]。但现有的治疗药物难以完全达到上述要求,这些药物具有非选择性降压的效果,往往造成低血压,从而使心、脑、肾供血不足,加重其缺血状态,而且多数药物在降低肺动
关键词(KeyWords)： 肺动脉高压;心肺功能;川芎嗪;综述
基金项目(Foundation):
作者(Author): 马德娴,熊旭东
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