中药调节TLR4信号通路治疗脓毒症肺损伤的研究进展
阚诗云,邓兆岿,邱占军
摘要(Abstract):
梳理中医对脓毒症肺损伤的认识、治疗原则、TLR4信号通路与脓毒症肺损伤的关系;综述近10年中药调节TLR4信号通路治疗脓毒症肺损伤的研究进展,重点分析中药复方、中药提取物通过对TLR4以及其下游信号分子的调节作用,从而提高脓毒症肺损伤治疗疗效,体现中医治疗脓毒症肺损伤优势,总结现阶段研究的优点,并对存在的问题及进一步的研究方向提出建议。
关键词(KeyWords): 脓毒症;脓毒症相关性肺损伤;TLR4信号通路
基金项目(Foundation): 山东省中医药科技发展计划项目(2015-091);; 济南市科技发展计划项目(201602184)
作者(Author): 阚诗云,邓兆岿,邱占军
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