肖阳春,李岩,王国庆,刘超,肖加斌

• 1:北京中医医院顺义医院

摘要(Abstract)：

目的观察升清降浊法治疗急诊脓毒症(正虚邪恋证)患者的临床效果。方法将92例脓毒症患者按随机数字表法分为治疗组与对照组,各46例,对照组给予西医常规治疗,治疗组在对照组治疗的基础上给予自拟升清降浊法治疗,两组都治疗观察7 d。结果治疗后治疗组与对照组的总有效率分别为91.30%和76.09%,治疗组明显高于对照组(P<0.05);治疗后治疗组与对照组的急性生理与慢性健康(APACHEⅡ)评分均明显低于治疗前(P<0.05),治疗组APACHEⅡ评分与对照组相比降低更加明显(P<0.05);治疗组与对照组治疗后的血清C反应蛋白(CRP)与降钙素原(PCT)值都明显低于治疗前(P<0.05),治疗组的血清CRP与PCT值也都明显低于对照组(P<0.05);治疗后治疗组的血清凝血酶原时间(PT)与活化部分凝血酶原时间(APTT)值都明显低于治疗前(P<0.05),治疗组PT与APTT对照组相比也明显降低(P<0.05)。结论升清降浊法治疗急诊脓毒症(正虚邪恋证)患者能降低APACHEⅡ评分,提高治疗效果,其作用机制可能与抑制炎症因子表达与改善凝血功能有关。

关键词(KeyWords)： 升清降浊法;正虚邪恋型;脓毒症;炎症因子;凝血功能

Abstract:

Keywords:

基金项目(Foundation): 首都医科大学中医感染性疾病基础研究北京市重点实验室开放课题项目(2015ZYGR02)

作者(Author): 肖阳春,李岩,王国庆,刘超,肖加斌

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