陈燕清,张红珍

• 1:山西中医学院

摘要(Abstract)：

目的利用高脂饲料诱发的动脉粥样硬化(AS)模型,观察补阳还五汤对C反应蛋白(CRP)的影响。方法大鼠造模成功后,随机分为4组:补阳还五汤组以补阳还五汤17.5g/(kg.d)灌胃;川芎嗪组给予川芎嗪0.2 g/(kg.d)灌胃;正常组及模型组喂普通饲料。用药30d后测定CRP、血脂。结果高脂饮食可诱导大鼠形成AS模型,模型组的血脂明显高于正常组。补阳还五汤组CRP、总胆固醇、甘油三酯、低密度脂蛋白水平均显著低于川芎嗪组、模型组。结论补阳还五汤具有抗AS作用,降低CRP和血脂可能是其作用机制之一。

关键词(KeyWords)： 动脉粥样硬化;补阳还五汤;C反应蛋白;益气活血

Abstract:

Keywords:

基金项目(Foundation): 山西省卫生厅科技攻关项目(200958)

作者(Author): 陈燕清,张红珍

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