劳杨骏,徐涛涛,杨笑奇,吴承亮

• 1:浙江中医药大学骨伤研究所
• 2:浙江省骨伤研究所
• 3:浙江中医药大学第一临床医学院
• 4:浙江中医药大学附属第一医院

摘要(Abstract)：

<正>椎间盘退变是临床上造成腰腿痛的主要原因[1],由于目前其发病机制尚未阐明,临床上的治疗手段相对单一,治疗效果不甚理想。动物模型是为生物医学研究和阐明人类疾病的病因、病机和探寻治疗方法而制作的实验动物。目前,能准确模拟人类椎间盘退变的动物模型尚不多见,选择和建立一种理想的椎间盘退变动物模型是研究其发病机制的关键。小鼠是品种最多,用途最广,研究最详尽的实验动物,拥有生长周期短,饲养管理方便,容易达到标准化

关键词(KeyWords)： 椎间盘退变;模型构建;动物实验

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(81273770);; 浙江省中西医结合骨关节病研究科技创新团队(2011R50022);; 浙江省骨关节疾病中医药干预技术研究重点实验室(2013E10024)

作者(Author): 劳杨骏,徐涛涛,杨笑奇,吴承亮

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