叶丽莎;白雪;张德绸;

• 1:西南医科大学附属中医医院

摘要(Abstract)：

目的 探讨祛风通窍方治疗后循环短暂性脑缺血发作（TIA）的疗效及对血管内皮功能的影响。方法选取后循性TIA患者110例为研究对象，采用随机数字表法分成观察组与对照组各55例。对照组患者均参照指南予以西医基础治疗措施，观察组患者在对照组治疗基础上采用祛风通窍方治疗，两组均治疗1周为1个疗程，连续2个疗程。比较两组临床疗效、中医证候评分、血液流变学指标、血管内皮功能指标和超声检查指标，并记录随访期间复发情况和不良反应发生情况。结果 相较于对照组，观察组临床总有效率明显更高（P <0.05）。相较于对照组，观察组治疗后中医证候评分、血液流变学指标水平下降程度更明显，ET-1、TXB2、vWF水平显著低于对照组，DR水平、Qmean、Vmean水平显著优于对照组，复发率明显低于对照组（P <0.05）。结论 祛风通窍方治疗后循环TIA的疗效良好，有助于改善患者中医证候评分和血液流变学指标，促进患者血管内皮功能恢复，改善脑部动力学指标，降低复发率。

关键词(KeyWords)： 后循环短暂性脑缺血发作;血管内皮功能;祛风通窍方

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 叶丽莎;白雪;张德绸;

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