健胃愈疡颗粒对胃溃疡大鼠胃黏膜氨基己糖及磷脂含量的实验研究The Experimental Study on Jianweiyuyang Granule on the Contents of Aninohexose and Phosphatide in Ulcerated Gastric Mucosa
黄国栋,李家邦,戴幸平,蒋容鑫,凌江红,黄媛华,黄道富,唐丽君,张曙,李倩
摘要(Abstract)：
目的观察健胃愈疡颗粒对胃溃疡大鼠胃黏膜氨基己糖及磷脂含量的影响,从而探讨其抗溃疡复发作用的机制。方法拟Okabe改良法制作SD大鼠胃溃疡模型,腹腔注射白介素-1β(IL-1β)制作胃溃疡复发模型;测定大鼠胃黏膜组织中磷脂和氨基己糖的含量。结果在灌胃第10日和第90日,健胃愈疡组磷脂和氨基己糖的含量显著高于模型组和正常对照组。结论健胃愈疡颗粒剂抗复发的作用机理可能与影响胃黏膜的疏水性有关。
关键词(KeyWords)： 健胃愈疡颗粒;胃溃疡;胃黏膜;疏水性;大鼠
基金项目(Foundation):
作者(Author): 黄国栋,李家邦,戴幸平,蒋容鑫,凌江红,黄媛华,黄道富,唐丽君,张曙,李倩
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