刺血醒脑法对急性脑梗死患者血清IL-1β、hs-CRP、TNF-α的影响Effect of Blood-pricking and Brain-activating Therapy on Serum IL-1β,hs-CRP and TNF-α in Patients with Acute Cerebral Infarction
王泽琴,米秀娟,陶文强,舒建中,李陈渝,赵玉华,龚廷亮,罗文澜,唐军
摘要(Abstract):
目的观察刺血醒脑法对急性脑梗死患者血清白细胞介素-1β(IL-1β)、超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)的影响并探讨其作用机制。方法患者60例随机分为两组,对照组给予指南规范化的西医治疗与西医康复治疗,观察组在对照组治疗基础上加用刺血醒脑法。观察两组患者治疗前后血清IL-1β、hs-CRP、TNF-α水平,并进行美国国立卫生研究院卒中量表(NIHSS)评价临床疗效。结果治疗后两组ACI患者血清IL-1β、hs-CRP、TNF-α水平均低于治疗前(P <0.05),且观察组低于对照组(P <0.05);治疗后两组较治疗前NIHSS评分均下降(P <0.05),且观察组低于对照组(P <0.05);观察组临床总有效率为86.00%,显著优于对照组的76.00%(P <0.05)。结论刺血醒脑法可以降低急性脑梗死患者血清IL-1β、hs-CRP、TNF-α水平,抑制血管炎性反应。
关键词(KeyWords): 急性脑梗死;刺血醒脑法;针刺
基金项目(Foundation): 重庆市社会事业与民生保障科技创新专项项目(重点)子课题(csts2016shms-zd10001-13)
作者(Author): 王泽琴,米秀娟,陶文强,舒建中,李陈渝,赵玉华,龚廷亮,罗文澜,唐军
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