代谢组学应用于冠心病中医辨证分型的研究进展
李静,李亮,杨萍,吴华英,袁志鹰,钟森杰,黄惠勇
摘要(Abstract):
代谢组学作为一门新兴的系统生物学技术,现广泛应用于冠心病的实验和临床研究。本文通过检索近年来冠心病代谢组学研究的相关文献,对冠心病诊断及中医辨证分型的代谢组学特征变化进行归纳总结,发现冠心病中医辨证分型的代谢表型存在差异,为探讨冠心病的病理机制、中医证型和治疗作用机理提供辅助诊断依据。
关键词(KeyWords): 冠心病;代谢组学;中医辨证;生物标志物;综述
基金项目(Foundation): 国家自然科学基金项目(81373551,81603512,81874429);; 湖南省自然科学基金项目(2019JJ40214);湖南省自然科学基金青年项目(2019JJ50446);; 湖南省教育厅重点项目(19A380);; 湖南省中医药科研计划重点项目(202004)
作者(Author): 李静,李亮,杨萍,吴华英,袁志鹰,钟森杰,黄惠勇
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