何梦吟,祝韵薇,鲁盈

• 1:浙江中医药大学附属浙江省立同德医院

摘要(Abstract)：

目的探讨舌象与痛风炎症活动度的关系,为中医药防治痛风提供新思路。方法采用前瞻性研究方法,共纳入原发性痛风患者120例,其中急性期80例,缓解期40例。对舌象资料量化积分,对比急性期与缓解期舌象特征,并探讨舌象积分与炎症指标的相关性。结果急性期组红舌、黄苔、腻苔和滑苔的出现率高于缓解期组,缓解期组淡白舌、白苔的出现率高于急性期组(P <0.05)。Logistic回归模型提示黄苔、腐腻苔、胖舌均是痛风急性发作的正相关影响因素,黄苔时痛风急性发作的概率是白苔时的117.047倍。急性期的舌象特征如红舌、黄苔、腻苔积分与血沉、超敏C反应蛋白、NLRP3炎症体、白细胞介素-1β呈正相关。结论舌诊在判断痛风的炎症活动度,及预测痛风急性发作方面有一定的诊断价值和规律性。

关键词(KeyWords)： 原发性痛风;中医诊断;舌诊;炎症;NLRP3;IL-1β

Abstract:

Keywords:

基金项目(Foundation): 浙江省医药卫生科技项目(2017200207)

作者(Author): 何梦吟,祝韵薇,鲁盈

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