痰热清注射液对COPD急性发作期患者血清IL-13、LTB-4表达和肺功能的影响Effect of Tanreqing Injection on the Serum IL-13,LTB-4 Expression and the Lung Function of COPD Patients with Acute Episode
刘永生,段莉,周成鸿
摘要(Abstract):
目的探讨痰热清注射液配合常规疗法治疗慢性阻塞性肺疾病(COPD)急性发作的疗效及其作用机制。方法将COPD急性发作期患者随机分为两组,均予西医常规治疗,联用组加用痰热清注射液,观察两组临床疗效并检测患者血清IL-13、LTB-4的含量和肺功能变化。结果联用组显效率明显高于常规组,对血清IL-13、LTB-4及肺功能的改善情况亦优于常规组。结论在常规疗法的基础上联用痰热清注射液治疗COPD急性发作能明显提高临床疗效,这可能与痰热清注射液能明显降低患者IL-13和LTB-4的分泌,减轻由其活化所致的炎症反应,改善肺功能有关。
关键词(KeyWords): 慢性阻塞性肺疾病;痰热清注射液;IL-13;LTB-4
基金项目(Foundation): 重庆医科大学科研项目(2010063)
作者(Author): 刘永生,段莉,周成鸿
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