“肺肠同治”在骨创伤后ARDS患者呼吸与肠屏障功能障碍中的应用及疗效评价Therapeutic Evaluation of Lung and Intestine Concurrent Therapy in Respiratory and Intestinal Barrier Dysfunction of ARDS Patients after Orthopedic Trauma
尤莉莉,刘燕,杨铁柱,李良业
摘要(Abstract):
目的观察"肺肠同治"干预治疗骨创伤后急性呼吸窘迫综合征(ARDS)患者呼吸与肠屏障功能的作用。方法 60例ARDS患者随机分为对照组和中药组,各30例。对照组采用西医常规治疗,中药组在对照组基础上加用通腑净化汤。观察治疗前和治疗后第3、7日两组呼吸和肠屏障功能相关指标改善情况。结果治疗后中药组患者呼吸功能和肠屏障功能改善程度明显优于对照组(P<0.05);治疗后中药组炎性指标改善明显优于对照组(P<0.05);治疗后中药组呼吸次数、影像学、大便难等临床疗效明显优于对照组(P<0.05)。结论通腑净化汤能有效改善骨创伤后ARDS患者呼吸与肠屏障功能障碍,调控炎性反应,提高临床疗效。
关键词(KeyWords): 急性呼吸窘迫综合征;通腑净化汤;肺肠同治
基金项目(Foundation): 河南省中医药科学研究专项课题(2013zy02010)
作者(Author): 尤莉莉,刘燕,杨铁柱,李良业
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