益肺康心胶囊对大鼠肺心病模型bFGF的影响Influence of Yifeikangxin Capsule on bFGF of Rats Model with Corpulmonale
梁群,蒋希成,吴海坤
摘要(Abstract):
目的探讨益肺康心胶囊对大鼠肺心病模型碱性成纤维细胞生长因子(bFGF)的影响。方法将60只SD大鼠分为空白组、模型组、中药组、对照组,每组15只。治疗组给予益肺康心胶囊,对照组给予卡托普利,每日1次。连续给药15d,至检查前24h停药。分别于停药后的7、14、28d处死大鼠,作肺组织bFGF测定。结果治疗组经益肺康心胶囊治疗后肺组织bFGF表达明显下降,低于模型组。结论益肺康心胶囊可明显抑制大鼠肺心病模型bFGF的表达。
关键词(KeyWords): 肺心病;益肺康心胶囊;碱性成纤维细胞生长因子;肺血管重构
基金项目(Foundation): 黑龙江省中医管理局科研项目(ZHY08-W45)
作者(Author): 梁群,蒋希成,吴海坤
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