创伤性颈髓损伤合并肺炎相关评分系统预测价值及中医证型分布的回顾性研究A Retrospective Study on the Predictive Value of Scoring System Related to Traumatic Cervical Spinal Cord Injury with Pneumonia and the Distribution of TCM Syndrome Types
杨铁柱,刘燕,徐道志,王茜,何冬梅,王凤英
摘要(Abstract):
目的探讨创伤性颈髓损伤合并肺炎相关评分系统的预测价值,以及中医证型分布和演变特点。方法 216例患者采用回顾性研究方法,根据是否合并肺炎,分为感染组和非感染组,绘制受试者工作特征曲线(ROC),评价美国脊椎损伤协会分级(ASIA)运动和感觉、急性生理与慢性健康(APACHEⅡ)评分、损伤严重程度(ISS)评分、临床肺炎(CPIS)评分对肺炎的预测价值;记录并统计分析肺炎患者中医证型及演变过程和不同ASIA级别的中医证型。结果感染组ASIA运动和感觉评分、APACHEⅡ评分、ISS评分、CPIS评分与非感染组差异具有统计学意义(均P <0.05);ROC曲线绘制发现,感染组患者在CPIS评分中,AUC面积最大,敏感性最高,特异性较高;感染组ASIA分级以A、B、C 3级居多,以痰热壅肺、痰湿壅肺、肺脾气虚为主,初期4例变证患者ASIA分级均为A级;发病初期,肺炎证型分布为痰热壅肺>痰湿壅肺>肺脾气虚>气阴两虚>(风热袭肺、热入心包、邪陷正脱)>外寒内热,痰热壅肺证(29.51%)最多;疾病中后期肺脾气虚、气阴两虚居多,痰热壅肺证和痰湿壅肺证减少;常见证型中6例恶化,转变为热入心包证和邪陷正脱证,变证中3例恶化。结论创伤性颈髓损伤合并肺炎患者,通过相关评分系统合理预测,并研究其证型分布及演变规律,掌握证候学规律,为合理使用中医药提供一定依据。
关键词(KeyWords): 创伤性颈髓损伤;肺炎;评分系统;中医证型;演变规律
基金项目(Foundation): 河南省中医药科学研究专项课题(2019ZY1031;2013zy02010)
作者(Author): 杨铁柱,刘燕,徐道志,王茜,何冬梅,王凤英
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