痰热清注射液治疗慢性阻塞性肺疾病急性加重患者疗效观察
向志,何微,贺兼斌,谢茂峰
摘要(Abstract)：
目的观察痰热清注射液在慢性阻塞性肺疾病急性加重住院患者中的治疗效果并探讨其作用机制。方法患者120例随机分为两组,观察组患者按照GOLD指南进一步分为B、C、D组。对照组仅采取西医常规治疗,观察组在对照组基础上应用痰热清注射液治疗。观察记录治疗前后各组患者肺功能和血气分析相关指标变化,比较住院时间、症状评分以及治疗期间不良反应发生率。结果治疗后两组第1秒呼气容积占预计值百分比(FEV1%)、动脉血氧分压(PaO2)水平高于治疗前(P <0.05),PaCO2低于治疗前(P <0.05),且观察组优于对照组(P <0.05),且B组和D组优于C组(P <0.05)。观察组患者平均住院时间与症状评分均低于对照组(P <0.05)。观察组轻微不良反应发生率低于对照组(P <0.05)。结论在西医常规治疗基础上应用痰热清注射液治疗慢性阻塞性肺疾病急性加重患者疗效显著,尤其适用于GOLD指南中慢阻肺急性加重B组和D组患者,有利于改善其临床症状、缩短治疗时间,且不良反应较少,对患者病情恢复具有重要意义。
关键词(KeyWords)： 慢性阻塞性肺疾病;急性加重期;疗效;不良反应;痰热清注射液
基金项目(Foundation):
作者(Author): 向志,何微,贺兼斌,谢茂峰
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