高血压性脑出血的中西医治疗
赵芳芳,徐敏,王平平,高利
摘要(Abstract):
<正>脑出血发病率大约占脑血管病的10%~15%,随着影像学的发展,更加细微的出血亦可能被检测到,这意味着本病的发生率可能会随着人口的增长而增长[1]。统计分析表明,我国高血压脑出血约占全部脑出血的
关键词(KeyWords): 高血压性脑出血;中医;西医;活血化瘀
基金项目(Foundation): 北京市科技计划科技工作基础专项基金资助项目(ZXW-2011-16)
作者(Author): 赵芳芳,徐敏,王平平,高利
参考文献(References):
- [1]Broderick JP,Brott T,Tomsick T,et al.Intracerebral hemor-rhage more than twice as common as subarachnoid hemor-rhage[J].J Neurosurg,1993,78:188-191.
- [2]Counsell C,Boonyakarnkul S,Dennis M,et al.Primary intrac-erebral haemorrhage in the oxfordshire community stroke pro-ject,2:prognosis[J].Cerebrovasc Dis,1995,5:26-34.
- [3]Broderick J,Connolly S,Feldmann E,et al.Guidelines for themanagement of spontaneous intracerebral hemorrhage inadults:2007 update:a guideline from the american heartAssociation/American stroke association stroke council,highblood pressure research council,and the quality of care andoutcomes in research interdisciplin-ary working group[J].stroke,2007,38:2001-2023.
- [4]Bereczki D,Fekete I,Prado GF,et al.Mannitol for acutestroke[J].Cochrane Database Syst Rev,2007(3):CD001153.
- [5]Anderson CS,Huang Y,Wang JG,et al.Intensive blood pres-sure reduction in acute cerebral haemorrhage trial(INTER-ACT):a randomized pilot trial[J].Lancet Neurol,2008,7:391-399.
- [6]Qureshi AI,Palesch YY.Effect of systolic blood pressure re-duction on hematoma expansion,perihematomal edema,and3-month outcome among patients with intracerebral hemor-rhage:results from the antihypertensive treatment of acutecerebral hemorrhage study[J].Arch Neurol,2010,67(5):570-576.
- [7]Mayer SA,Brun NC,Begtrup K,et al.FAST trial investigators.Efficacy and safety of recombinant activated FactorⅦfor a-cute intracerebral hemorrhage[J].N Engl J Med,2008,358(20):2127-2137
- [8]Naidech AM,Garg RK,Liebling S,et al.Ant iconvul sant useand out comes after intracer ebral hemorrhage[J].Stroke,2009,40(12):3810-3815.
- [9]Okauchi M,Hua Y,Keep RF,et al.Deferoxamine treatmentfor intracerebral hemorrhage in aged rats:therapeutic timewindow and optimal duration[J].Stroke,2010,41(2):375-382.
- [10]曹忠义,高颂.活血化瘀法对急性脑出血血液流变学及颅内血肿吸收的影响[J].中国中医急症,2001,10(1):24.
- [11]唐宇平,蔡定芳,刘军,等.大黄改善急性脑出血大鼠血脑屏障损伤的水通道蛋白-4机理研究[J].中国中西医结合杂志,2006,26(2):152-156.
- [12]Schiller H,Bartscht,Arh A,et al.Thrombin as a survival fac-tor for cancer cells:thrombin activation in malignant effusionsin vivo and inhibition of idarubicin-induced cell death invitro[J].Int J Clin Pharmacol Ther,2002,40(8):329-335.
- [13]谢道珍,项宝玉,孙怡,等.脑血疏口服液治疗出血性中风的临床研究[J].中西医结合心脑血管病杂志,2007,5(8):690-691.
- [14]Mayer SA,Lignelli A,Fink ME,et al.Perilesional blood flowand edema formation in acute intracerebral hemorrhage:aSPECT study[J].Stroke,1998,29(9):1791-1798.
- [15]杨万章,高利.对脑出血后继续出血及活血化瘀时间窗问题的讨论[J].中国中西医结合急救杂志,2005,12(3):190-192.
- [16]Nagatsuna T,Nomura S,Suehiro E,et al.Systemic adminis-tration of argatroban reduces secondary brain damage in a ratmodel of intracerebral hemorrhage:histopathological assess-ment[J].Cerebrovasc Dis,2005,19(3):192-200.
- [17]Kitaoka T,Hua Y,Xi G,et al.Effect of delayed argatrobantreatment on intracerebral hemorrhage-induced edema in therat[J].Acta Neurochir Suppl,2003,86:457-461.
- [18]Morgenstern LB,Demchuk AM,Kim DH,et al.Rebleedingleads to poor outcome in ultra-early craniotomy for intracere-bral hemorrhage[J].Neurology,2001,56:1294-1299.
- [19]Teernstra OP,Evers SM,Kessels AH.Meta analyses in treat-ment of spontaneous supratentorial intracerebral haema-toma[J].Acta Neurochir(Wien),2006,148:521-528.
- [20]Mendelow AD,Gregson BA,Fernandes HM,et al.Earlysurgery versus initial conservative treatment in patients withspontaneous supratentorial intracerebral haematomas in theinternational surgical trial in intracerebral haemorrhage(STICH):a randomised trial[J].Lancet,2005,365:387-397.
- [21]Morgan T,Awad I,Keyl P,et al.Preliminary report of the clotlysis evaluating accelerated resolution of intraventricularhemorrhage(CLEAR-IVH)clinical trial[J].Acta NeurochirSuppl,2008,105:217.
- [22]Gauthier LV,Taub E,Perkins C,et al.Remodiling the brain:plastic structural brain changes produced by different motortherapies after stroke[J].Stroke,2008,39(5):1520-1525.