丹参化瘀汤联合导管接触溶栓治疗急性期下肢深静脉血栓形成的临床观察Clinical Study of Danshen Huayu Decoction Combined with Catheter Contact Thrombolysis in the Treatment of Acute Deep Venous Thrombosis of Lower Extremity
龚心军,李昌剑,车艾青
摘要(Abstract):
目的 观察丹参化瘀汤联合导管接触溶栓(CDT)治疗急性期下肢深静脉血栓形成(LDVT)的临床效果。方法 患者86例采用随机数字表法将其分为观察组与对照组各43例。对照组患者予以CDT治疗,观察组患者在对照组治疗基础上采用丹参化瘀汤口服。比较两组临床症状评分、白细胞计数(WBC)、D-二聚体(D-D)水平、患肢与健侧肢体周径差和综合疗效。结果 相较于对照组,观察组治疗后患肢疼痛、患肢肿胀、皮肤色泽、彩超得分明显更低,WBC、D-D水平明显更低(P <0.05)。观察组髌骨上15 cm周径差和胫骨粗隆下10 cm周径差明显高于对照组(P <0.05)。观察组临床总有效率为93.02%,明显高于对照组的76.74%(P <0.05)。结论 丹参化瘀汤联合CDT治疗急性期LDVT疗效良好,可改善患者的疼痛肿胀感和皮肤色泽,降低WBC、D-D水平。
关键词(KeyWords): 下肢深静脉血栓形成;急性期;丹参化瘀汤;导管接触溶栓
基金项目(Foundation): 重庆市南川区科技计划项目(CX202032)
作者(Author): 龚心军,李昌剑,车艾青
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